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CRISPR Gene editing therapy is used for the first time in living humans with amazing results.

0:00 Introduction
0:53 What is CRISPR?
2:05 How Does CRISPR work?
3:18 The Experiment
5:30 The Results
9:31 Shortcomings
10:34 The Future
12:00 Caution
13:02 Conclusions

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Sources:

https://theconversation.com/what-is-crispr-gene-editing-and-how-does-it-work-84591

https://www.newscientist.com/definition/what-is-crispr/#ixzz7AeYFNfd1

Research paper: https://journals.lww.com/retinajournal/_layouts/15/oaks.journals/downloadpdf.aspx?an=00006982-202105000-00002&pdfToken=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

https://futurism.com/neoscope/gene-therapy-injected-eyeball-restores-blind-patients-vision

https://www.vox.com/2018/7/23/17594864/crispr-cas9-gene-editing

https://www.npr.org/sections/health-shots/2021/09/29/1040879179/vision-loss-crispr-treatment

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48 thoughts on “BREAKTHROUGH: Scientists Reverse Blindness [CRISPR Technology]

  1. What is defined as a disease is my concern, can you recall homosexuality defined as a pathological disorder? Hitler and racial hygiene? Why were alternative races defined as diseases? Humans clearly cannot be trusted, they will no doubt abuse people with it with selfish motives.
    I am autistic and I don't want to be cured of the gifts that come with it, they should not have the right to change people without our consent, it is racism and discrimination.

    Molecular biologist Miroslav Radman writes, "Mutagenesis has traditionally been viewed as an unavoidable consequence of imperfections in the process of DNA replication and repair. But if diversity is essential to survival, and if mutagenesis is required to generate such diversity, perhaps mutagenesis has been positively selected for throughout evolution."

    Evelyn Fox Keller explains:
    "We now know that mechanisms for enduring genetic stability are a product of evolution. Yet a surprising number of mutations in which at least some of these mechanisms are disabled have been found in bacteria living under natural conditions. Why do these mutants persist? Is it possible that they provide some selective advantage to the population as a whole? Might the persistence of some mutator genes in a population enhance the adaptability of that population? Apparently so. New mathematical models of bacterial populations in variable environments confirm that, under such conditions, selection favors the fixation of some mutator alleles and furthermore, that their presence accelerates the pace of evolution."

    The mutants behind autism offer some great advantages to the human race, diminishing the genes is a great risk because without those mechanisms there is no asurety of genetic stability pushing us in the direction of extinction.

    Psychologist Howard Gardner warns:
    "With the coming of age of genetics, the danger magnifies. Beyond doubt we will discover genes that are important for reading alphabetical scripts; and there is already evidence that a small set of genes may be related to reading problems. As with the brain evidence, such information can be helpful for early intervention; but it could easily be used for stigmatising purposes. Indeed, it might become relevant for marriage prospects, holding a job, securing insurance, or even eugenic purposes. And no doubt, especially in our interventionist society, individuals with a genetic predisposition for reading problems will look into different kinds of genetic engineering or therapy. It is possible that such interventions will work and have no negative side effects, but it is perhaps more likely that they will have unanticipated effects. And we might even want to consider which valued human abilities – eg. spatial or pattern recognition skills – might be placed at risk were we to target our interventions specifically at reading disorders."

    We can see the vast majority of so called diseases for what they are; they are discriminatory social constructions, not an intention to objectively understand human biology.
    Were global warming, warmer oceans, production of epidemic diseases, climate change, increased natural hazards and more anticipated. I doubt it so I would say Howard Gardner has a good point, every time humans have tried to play God and control nature nature struck humans back with greater problems, the people trying to solve the problems are the people who caused the problems and are trying to solve those problems repeating the same mistake to cause more problems.
    Why do so called geniuses fail to recognise their own short comings, why aren't we trying to cure the majority's weaknesses and how sickening the majority is with its ableism?

  2. "Sarif was right about one thing. It's in our nature to want to rise above our limits. Think about it. We were cold, so we harnessed fire. We were weak, so we invented tools. Every time we met an obstacle, we used creativity and ingenuity to overcome it." —Deus Ex: Human Revolution

  3. It becomes biblical.
    Jesus Christ is coming again very soon to rapture his church. Then the Antichrist comes onto the world stage with his illusion of peace and with him hell on earth. Unfortunately, too many people will fall for it.
    Read Revelation and the Gospel of John.

    Jesus Christ is God. Turn back to him. Ask forgiveness of your sins. Believe in the gospel.

    Religions do not come from God.
    In Jesus Christ alone we have salvation and salvation.

    God's blessings and protection and peace in the name of Jesus Christ

  4. I bet it’s possible for crisper to be used for evil. If it got into the wrong hands. I could think of multiple ways it could be incredibly dangerous.

  5. I'm the opposite of religion believe me.
    But this is literally playing god.
    And as always with every great invention comes abuse.
    So we have to ask ourselves where do we stop?
    Just to give you a perfect example:
    We restricted the a.i with weapon laws so it can't kill us.
    And ironically the most powerful country in A.I China makes a drone dog with a weapon on it.
    Where does it end?

  6. There are so many problems this technology can solve! Sure, few think that this like playing god, but the internet already did that, and improving a baby's life is not playing god, because then things like vaccines may also be called playing god, but alas some people oppose that too.

  7. The technology is abused then used throughout the history. They will genetically modify humans, means more intelligent, more powerful, ageless, will rule/slave other humans.

  8. Alhamdulillah الحمدلله
    I THANK ALLAH for opening this up AND that HE ALLOWED it to COME TO REALITY at YOUR HANDS ….

    ذلك فضل الله يؤتيه من يشاء والله ذو الفضل العظيم!!

    إن الله تعالى هو خالق كل ذرة من الذرات وكل فرد من أفراد الكائنات،  وهو مالكُهم ، والقادر عليهم ، وهو القادر سبحانه أن يبدلهم،  أو يبدل أحوالهم كيف يشاء سبحانه،  له الملك وله الحمد،  يجتبي مَن يشاء،  ويهدي إليه من يُنيب ، وينصر من نصره ، ويرحم الرحماء من عباده ، ويعز من أقام أمره بالإحسان،  ويفعل ما يريد سبحانه
    اللهم أنت خلقتنا وأنت تهدينا وأنت تطعمُنا وأنت تسقينا وأنت تميتنا وأنت تحيينا لا إله إلا أنت وحدك لا شريك لك الملك لك الحمد والشكر وأنت على كل شيء قدير

  9. I am both excited for this. Although their will be many who don't want it around because of their own bias and interests. Can you imagine if you could fix/prevent being g A y. The cultural implications are huge.

  10. Southeast Asians must use crispr technology… height and dix are very small in there!… Koreans too..for they have a growing penis..but still not enough!.. higher latitudes are having people whose chests are not upto the mark due to deficiency of energy available.. therefore, this technology will definitely help in boosting the chest growth in males very much

  11. I'm am severely visually impaired myself after a generic disease caused my vision to plummet off a cliff a few years ago, just as I finished university. This really gives me hope, if I can get back even a small percentage of what I lost, I'll take it.

  12. 13 months of good eyesight. Sounds like a pharmeceutical gold mine. Big Pharma won't want to cure the disease, they want people to cope with it. They want people to keep coming back to get treatment and generate huge profits. THey can monetize blindness prevention. Heaven forbid if they can make the treatment permanent and they eliminate the diease and all its money making potential altogether. 5:20

  13. This really is something positive and something to which we can look forward in the future! Short of creating a workable/viable bionic eye (which I think is somewhere on the horizon – it just stands to reason that eventually technology will move up to the point where a literal manufactured bionic I can be attached completely successfully to the mechanism that we now have connecting our eyes to vision centers in the human brain) this seems like tremendously wonderful progress in the right direction.

    Now the silly part of my comment:

    I can see (no pun intended) that the most vital use of this technology (or at least most fun?) Is to have it create for me a glowing rabbit.

    And now a non sequitur addendum to my comment:

    I like eggs.

  14. CRISPR is incredible and has virtually limitless applications. Ultimately it doesn't matter if some people are up in arms about it's ethical implications, nothing can stop the research now, it has too much promise to be stopped.

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