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Chris McCurdy is a pharmaceutical scientist and pharmacist whose research focuses on the design, synthesis and development of drugs to treat pain and drug abuse. His latest research investigates a naturally occurring molecule that may regulate an enzyme which helps produce the powerful psychedelic compound dimethyltryptamine, or DMT, in the body.

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EPISODE LINKS
https://pharmacy.ufl.edu/profile/mccurdy-christopher
https://pubmed.ncbi.nlm.nih.gov/?term=McCurdy+CR&cauthor_id=33213215

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LISTEN ON
Spotify – https://open.spotify.com/show/4VTLG0HiIZaCjH9gE6NFPq
Apple – https://itunes.apple.com/podcast/id1441238966

OUTLINE
00:00 – The most hallucinogenic plant in existence
09:39 – Natural DMT in our bodies & schizophrenia
19:43 – Finding DMT in spinal fluid
27:06 – Endogenous tripping & transcendental meditation
37:26 – Placebo effect & treating cancer with the brain
47:08 – The flaw in the “healthcare equation”
57:18 – Why coca leaves should be legal
01:13:44 – Only 3 countries where coca leaves are legal
01:17:18 – Kratom’s dangerous trajectory
01:29:15 – World’s biggest kratom study
01:43:01 – 7 hydroxy products (7-OH) vs. kratom
01:47:12 – The drug with the deadliest withdrawal process
01:59:52 – Why ritalin shouldn’t be prescribed to kids
02:07:46 – How Modafinil works
02:14:55 – The kanna plant
02:20:02 – FDA finds how much kratom leads to overdose
02:28:12 – Different strains of kratom leaf

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47 thoughts on “Top Chemist Just Discovered How to Hack the Brains Internal DMT Molecule | Chris McCurdy

  1. You can just tell within 20 minutes of listening to this guy, that he's a good dude. Excellent guest Danny, great discussion. You just seem to ask the right questions dude, and coax out the most interesting conversation out of your guests..

  2. 1:56:56
    Opioid withdrawal has resulted in death actually, in several cases.
    2 of the most known cases happened in county jails, and were the result of essentially jail staff not giving a shit about inmate health and safety. They couldn’t be bothered to do anything about an inmate who was in severe opioid withdrawal, could not keep anything down food or water wise, and had severe diarrhea, which exacerbated the dehydration from constant vomiting even more so. The ultimate cause of death was dehydration, but said dehydration was the result of the symptoms of severe protracted opioid withdrawal, so really, the cause of death is opioid withdrawal.

    I’ve been through both opioid and benzodiazepine withdrawal, both are hell. The benzo withdrawal had me in a state where I truly don’t even remember much of it, as I had no clue what was going on, and eventually with the help of a medical detox after having to go to the ER because of a seizure, it became a much smoother process. Now opioid withdrawal was different, I’ve done cold turkey kicks many times, sometimes on purpose when I’d get a wild streak and decide I wanted to get off dope once and for all and for good, and I needed that kick in the ass of withdrawal pain as punishment and reason to not go back, and then of course I’ve been through it as a result of not having any more dope or money. I did suboxone maintenance on and off for many years, but then fentanyl became my drug of choice after it became much more prevalent, and regular heroin essentially dried up and became much harder to find and much more expensive. The withdrawal from fentanyl is a different beast, it gets into your fat, unlike other opioids, and makes the process very harsh. I eventually got to the point where I had tried so many things to stay clean over the years, all had failed, and there was one more thing that I hadn’t tried because so many people had bad things to say about it, methadone.
    It took a little bit, but I eventually got stable to the point where I was no longer using fentanyl, and the methadone covered all the withdrawal symptoms, and the physician was always ok with upping my dose if I needed. I’m now almost 2 years clean of fentanyl and all other street drugs, I take my methadone every day as prescribed, and because of that success, I have the highest level of take home privileges, so I only need to go to the clinic once a month. If I wanted to get off of it, my counselor and physician would be happy to start the taper process and support me all the way, I really lucked out and found an amazing clinic with amazing people. I have my life back, and I haven’t achieved this length of abstinence from street drugs since I was 19, I’m now 30. And I owe it all to methadone! If you’re in a similar spot where you’ve tried so many things and can’t get clean from heroin/fentanyl, don’t listen to whoever knocks it just because THEY didn’t have success with it, seriously, it can change your life.

  3. I bet RICHARD ALAN MILLER WAS AT THAT CONFERENCE! ALSO DMT IS IN THE BODY AS THE INTERFACE BETWEEN CONSCIOUSNESS AND FORM… THE KEY IS IN HOW DMT CRYSTALS LIGHT UP WHEN HIT… DMT IS IN THE PINEAL IN NANO FORM, AND THE ALKALINE H2O2 FILLED PINEAL PUTS PRESSURE ON THE CRYSTALS CREATING PHOTONIC SHAPES (IN THE "PINECONE" PINEAL) WHICH ARE AKIN TO THE HEBREW LETTERS, WHICH ARE THE HAND IN THE SHADDOW OF A CANDLE, BUT THESE SHAPES FORM THE CODING FOR THE MATRIX OF FORM, WHICH IS HOLOGRAPHIC.

  4. I belive that everyone should be able to grow a couple of weed plants, couple of opium poppy plants, and a coca bush. These would solve most basic at home medical needs and not be addictive. Smoke weed, poppy tea, and chewed coca, most people would be much calmer and happier.

  5. I am epileptic and I use marijuana because the seizure meds are so hard. It’s been 9 years now and I’m still alive doctors told me I would die in a few years. Natural is the way to go for me but may not work for some.

  6. You been in the game awhile it seems. Sorry to hear you aren’t familiar of the greatest Dr. To ever live that reversed 100s of dis eases through a study with mk Ultra. I present you Dr. Abram Hoffer. Niacininmide is his go-to!!

  7. first time listening mr. mccurdy and I'd say he's a talker as smooth and informative as hamilton morris who I followed through years on podcasts about psychoactive stuff.

  8. I get powdered kratom from the head shop and put some in a tea. One bag will last forever! No need to buy the expensive premade cans. Sorry Danny lol. Also, keep it in the freezer will keep it fresh a lot longer.

  9. I’ve been taking kratom 4 years now. Currently weaning off. I was having to take lot to feel it. I’m at the point I don’t even get nauseous from it. I started taking it for all the good reasons, I don’t like to high. I think it’s great for people that are constantly in pain and getting off opiates. But I wish I never started it. The withdrawals suck. If you’re not dealing with pain or coming off an opiate addiction stay away from it. If it gets abused it’ll ruin it for the people that do need it. If you use it for pain or coming off opiates make a tea out of it. And drink lots of water.

  10. Plenty of better solutions than radiation have been discovered to treat cancer. But it gets suppressed, slandered, or bought and shelved indefinitely.

  11. Kratom has been very good for my chronic pain. It also helps with my migranes from a tbi. I use it in its natural form. Off ALL narcotic Rx pain killers. NONE. THC has been a god send as well. People will say what they say. But I used to be precribed 80mg oxycontin and Fentynal patches for over 10yrs.

  12. Danny I can't believe I've never heard of you until recently. I've been binging your videos ever since I discovered you a few days ago. You're awesome I love your videos and guests so far!

  13. Finally. Another human being on planet earth that pronounces fentanyl correctly…. Can’t even get anyone at the hospital to pronounce it correctly lol. End rant.

  14. Dude doesn’t know what he’s talking about on multiple counts.

    First he says we have no idea why we make DMT in the body. False. It’s known to be protective to the brain against hypoxia. In other words, it allows the brain to survive for longer when it’s starved of oxygen.

    Second, he says modafinil operates only on orexin. False. It’s also a dopamine reuptake inhibitor which is why it lifts mood and is used off label for ADHD.

    Those two inaccuracies alone are enough to not trust this dude.

  15. Keep it under 15gdp and its like a miracle pick me up/pain duller, go over 30gdp and youll be pooping rocks and peeing everry 10 minutes cos your opioid receptots will be fried — keep it legal!

  16. Problem with Studies on Meth is they have change the way precursors are manufactured so it’s not the same any more there no euphoric rush when shooting it and heat in your glandular areas so studies and even legality is compromised seeing it’s no where near the same product anymore so it’ll have to be re studied this must of been a global effort otherwise drug from another country would still do this very much this sucks I liked the old meth where 15mg would be plenty or even as pure as 5mg now not even 200 mg would do this rush

  17. Title seems to be click bait 🤦‍♂️ nearly two hours in and nothing really about DMT or how to hack it 🤷‍♂️

  18. 10 days off methadone today, which i used to detox from Kratom which I used to detox from methadone which got me off fentanyl over 2 years ago but after over 15 years addicted to H Im finally free

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